NCR3 antibody (AA 20-140)

Catalog No. ABIN6144427

Product Details anti-NCR3 Antibody

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Binding Specificity: AA 20-140

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCR3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: WVSQPPEIRT LEGSSAFLPC SFNASQGRLA IGSVTWFRDE VVPGKEVRNG TPEFRGRLAP LASSRFLHDH QAELHIRDVR GHDASIYVCR VEVLGLGVGT GNGTRLVVEK EHPQLGAGTV L

Cross-Reactivity: Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-140 of human NCR3 (NP_667341.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NCR3

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Alternative Name: NCR3 (NCR3 Products)

Synonyms: MGC133750 antibody, 1C7 antibody, CD337 antibody, LY117 antibody, MALS antibody, NKp30 antibody, Nkp30 antibody, natural cytotoxicity triggering receptor 3 antibody, NCR3 antibody, Ncr3 antibody

Background: The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.,NCR3,1C7,CD337,LY117,MALS,NKp30,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,NCR3

Molecular Weight: 16 kDa/17 kDa/18 kDa/19 kDa/20 kDa/21 kDa

Gene ID: 259197

UniProt: O14931

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process