Myotilin antibody (AA 259-314)

Catalog No. ABIN6144297

Product Details anti-Myotilin Antibody

Target: Myotilin (MYOT)

Binding Specificity: AA 259-314

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myotilin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: RPNQTLPAPK QLRVRPTFSK YLALNGKGLN VKQAFNPEGE FQRLAAQSGL YESEEL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 259-314 of human MYOT (NP_001129412.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:10 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Myotilin

Target: Myotilin (MYOT)

Alternative Name: MYOT (MYOT Products)

Synonyms: LGMD1 antibody, LGMD1A antibody, MFM3 antibody, TTID antibody, TTOD antibody, 5530402I04Rik antibody, Ttid antibody, MYOT antibody, ttid antibody, myotilin antibody, MYOT antibody, Myot antibody, myot antibody

Background: This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.,MYOT,LGMD1,LGMD1A,MFM3,TTID,TTOD,myotilin,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,Cardiovascular,Heart,Contractility,MYOT

Molecular Weight: 35 kDa/55 kDa

Gene ID: 9499

UniProt: Q9UBF9