Myosin VIIA antibody (AA 850-1150)

Catalog No. ABIN6144293

Product Details anti-Myosin VIIA Antibody

Target: Myosin VIIA (MYO7A)

Binding Specificity: AA 850-1150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin VIIA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MIARRLHQRL RAEYLWRLEA EKMRLAEEEK LRKEMSAKKA KEEAERKHQE RLAQLAREDA ERELKEKEAA RRKKELLEQM ERARHEPVNH SDMVDKMFGF LGTSGGLPGQ EGQAPSGFED LERGRREMVE EDLDAALPLP DEDEEDLSEY KFAKFAATYF QGTTTHSYTR RPLKQPLLYH DDEGDQLAAL AVWITILRFM GDLPEPKYHT AMSDGSEKIP VMTKIYETLG KKTYKRELQA LQGEGEAQLP EGQKKSSVRH KLVHLTLKKK SKLTEEVTKR LHDGESTVQG NSMLEDRPTS N

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 850-1150 of human MYO7A (NP_000251.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Myosin VIIA

Target: Myosin VIIA (MYO7A)

Alternative Name: MYO7A (MYO7A Products)

Background: This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.,MYO7A,DFNA11,DFNB2,MYOVIIA,MYU7A,NSRD2,USH1B,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,MYO7A

Molecular Weight: 138 kDa/240 kDa/249 kDa/250 kDa/254 kDa

Gene ID: 4647

UniProt: Q13402

Pathways: Sensory Perception of Sound