Myosin VI antibody (AA 1016-1285)

Catalog No. ABIN6144291

Product Details anti-Myosin VI Antibody

Target: Myosin VI (MYO6)

Binding Specificity: AA 1016-1285

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin VI antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IAQSEAELIS DEAQADLALR RNDGTRPKMT PEQMAKEMSE FLSRGPAVLA TKAAAGTKKY DLSKWKYAEL RDTINTSCDI ELLAACREEF HRRLKVYHAW KSKNKKRNTE TEQRAPKSVT DYDFAPFLNN SPQQNPAAQI PARQREIEMN RQQRFFRIPF IRPADQYKDP QSKKKGWWYA HFDGPWIARQ MELHPDKPPI LLVAGKDDME MCELNLEETG LTRKRGAEIL PRQFEEIWER CGGIQYLQNA IESRQARPTY ATAMLQSLLK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1016-1285 of human MYO6 (NP_004990.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Myosin VI

Target: Myosin VI (MYO6)

Alternative Name: MYO6 (MYO6 Products)

Background: This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,MYO6,DFNA22,DFNB37,Myo6-007,Myo6-008,myosin VI,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,MYO6

Molecular Weight: 145 kDa/146 kDa/148 kDa/149 kDa

Gene ID: 4646

UniProt: Q9UM54

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization