Myosin IC antibody (AA 769-1028)

Catalog No. ABIN6144280

Product Details anti-Myosin IC Antibody

Target: Myosin IC (MYO1C)

Binding Specificity: AA 769-1028

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin IC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: ENAFFLDHVR TSFLLNLRRQ LPQNVLDTSW PTPPPALREA SELLRELCIK NMVWKYCRSI SPEWKQQLQQ KAVASEIFKG KKDNYPQSVP RLFISTRLGT DEISPRVLQA LGSEPIQYAV PVVKYDRKGY KPRSRQLLLT PNAVVIVEDA KVKQRIDYAN LTGISVSSLS DSLFVLHVQR ADNKQKGDVV LQSDHVIETL TKTALSANRV NSININQGSI TFAGGPGRDG TIDFTPGSEL LITKAKNGHL AVVAPRLNSR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 769-1028 of human MYO1C (NP_203693.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Myosin IC

Target: Myosin IC (MYO1C)

Alternative Name: MYO1C (MYO1C Products)

Background: This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19.,MYO1C,MMI-beta,MMIb,NMI,myr2,myosin IC,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,MYO1C

Molecular Weight: 117 kDa/119 kDa/121 kDa

Gene ID: 4641

UniProt: O00159

Pathways: Platelet-derived growth Factor Receptor Signaling