MYH7 antibody (AA 1766-1935)
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- Target See all MYH7 Antibodies
- MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))
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Binding Specificity
- AA 1766-1935
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MYH7 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- AEELKKEQDT SAHLERMKKN MEQTIKDLQH RLDEAEQIAL KGGKKQLQKL EARVRELENE LEAEQKRNAE SVKGMRKSER RIKELTYQTE EDRKNLLRLQ DLVDKLQLKV KAYKRQAEEA EEQANTNLSK FRKVQHELDE AEERADIAES QVNKLRAKSR DIGTKGLNEE
- Cross-Reactivity
- Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1766-1935 of human MYH7/beta-MHC (NP_000248.2).
- Isotype
- IgG
- Top Product
- Discover our top product MYH7 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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Hypoxia-Induced Mitogenic Factor Promotes Cardiac Hypertrophy via Calcium-Dependent and Hypoxia-Inducible Factor-1α Mechanisms." in: Hypertension (Dallas, Tex. : 1979), Vol. 72, Issue 2, pp. 331-342, (2018) (PubMed).
: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." in: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).
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Hypoxia-Induced Mitogenic Factor Promotes Cardiac Hypertrophy via Calcium-Dependent and Hypoxia-Inducible Factor-1α Mechanisms." in: Hypertension (Dallas, Tex. : 1979), Vol. 72, Issue 2, pp. 331-342, (2018) (PubMed).
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- Target
- MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))
- Alternative Name
- MYH7 (MYH7 Products)
- Synonyms
- CMD1S antibody, CMH1 antibody, MPD1 antibody, MYHCB antibody, SPMD antibody, SPMM antibody, Myhcb antibody, AMHC1 antibody, myosin antibody, myosin-7 antibody, B-MHC antibody, MyHC-I antibody, Myhc-b antibody, beta-MHC antibody, myosin heavy chain 7 antibody, myosin, heavy chain 7, cardiac muscle, beta antibody, myosin, heavy polypeptide 7, cardiac muscle, beta antibody, MYH7 antibody, Myh7 antibody
- Background
- Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.,MYH7,CMD1S,CMH1,MPD1,MYHCB,SPMD,SPMM,myosin-7,MYH7,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,MYH7
- Molecular Weight
- 223 kDa
- Gene ID
- 4625
- UniProt
- P12883
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