COX2 antibody (AA 100-200)
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- Target See all COX2 Antibodies
- COX2 (Cytochrome C Oxidase Subunit II (COX2))
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Binding Specificity
- AA 100-200
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This COX2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- MGHQWYWSYE YTDYEDLCFD SYMIPTNDLK PGELRLLEVD NRVVLPMELP IRMLISSEDV LHSWAVPSLG LKTDAIPGRL NQATVTSNRP GLFYGQCSEI C
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 100-200 of mouse MTCO2 (NP_904331.1).
- Isotype
- IgG
- Top Product
- Discover our top product COX2 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:100
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- COX2 (Cytochrome C Oxidase Subunit II (COX2))
- Alternative Name
- MT-CO2 (COX2 Products)
- Synonyms
- COX-2 antibody, Cox2 antibody, COII antibody, MTCO2 antibody, cox antibody, SC6G10.29c antibody, cCOII antibody, prostaglandin-endoperoxide synthase 2 antibody, cytochrome c oxidase subunit II antibody, COXII antibody, cytochrome c oxidase subunit ii antibody, cytochrome C oxidase subunit II antibody, cytochrome c oxidase subunit 2 antibody, cytochrome oxidase subunit 2 antibody, Ptgs2 antibody, COX2 antibody, Smed_0518 antibody, Mrub_0709 antibody, Ocepr_1683 antibody, SCO2156 antibody, coxB antibody, Dtpsy_2860 antibody, Ndas_3150 antibody, Mesil_0628 antibody, Bresu_0801 antibody, cox2 antibody
- Background
- Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII, ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII and cytochrome c oxidase (complex IV, CIV, that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS are transferred via the dinuclear copper A center (CU(A of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC formed by heme A3 and copper B (CU(B. The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.,MT-CO2,COII,MTCO2,COX2,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Mitochondrial markers,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,MT-CO2
- Molecular Weight
- 25 kDa
- Gene ID
- 17709
- UniProt
- P00403
- Pathways
- Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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