MRPS31 antibody (AA 66-395)

Catalog No. ABIN6144045

Product Details anti-MRPS31 Antibody

Target: MRPS31 (Mitochondrial Ribosomal Protein S31 (MRPS31))

Binding Specificity: AA 66-395

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS31 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Sequence: ICSKKDKQSV RTEETSKETS ESQDSEKENT KKDLLGIIKG MKVELSTVNV RTTKPPKRRP LKSLEATLGR LRRATEYAPK KRIEPLSPEL VAAASAVADS LPFDKQTTKS ELLSQLQQHE EESRAQRDAK RPKISFSNII SDMKVARSAT ARVRSRPELR IQFDEGYDNY PGQEKTDDLK KRKNIFTGKR LNIFDMMAVT KEAPETDTSP SLWDVEFAKQ LATVNEQPLQ NGFEELIQWT KEGKLWEFPI NNEAGFDDDG SEFHEHIFLE KHLESFPKQG PIRHFMELVT CGLSKNPYLS VKQKVEHIEW FRNYFNEKKD ILKESNIQFN

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 66-395 of human MRPS31 (NP_005821.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MRPS31

Target: MRPS31 (Mitochondrial Ribosomal Protein S31 (MRPS31))

Alternative Name: MRPS31 (MRPS31 Products)

Synonyms: IMOGN38 antibody, MRP-S31 antibody, S31mt antibody, 1500002D03Rik antibody, AA960481 antibody, Imogen38 antibody, Imogen44 antibody, mitochondrial ribosomal protein S31 antibody, MRPS31 antibody, Mrps31 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes, however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13.,MRPS31,IMOGN38,MRP-S31,S31mt,Epigenetics & Nuclear Signaling,RNA Binding,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitochondrial translation,Immunology & Inflammation,MRPS31

Molecular Weight: 45 kDa

Gene ID: 10240

UniProt: Q92665