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MRPS12 antibody (AA 30-138)

MRPS12 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6144024
  • Target See all MRPS12 Antibodies
    MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))
    Binding Specificity
    • 8
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-138
    Reactivity
    • 32
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 31
    • 1
    Rabbit
    Clonality
    • 32
    Polyclonal
    Conjugate
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MRPS12 antibody is un-conjugated
    Application
    • 25
    • 18
    • 14
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    MATLNQMHRL GPPKRPPRKL GPTEGRPQLK GVVLCTFTRK PKKPNSANRK CCRVRLSTGR EAVCFIPGEG HTLQEHQIVL VEGGRTQDLP GVKLTVVRGK YDCGHVQKK
    Cross-Reactivity
    Human
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 30-138 of human MRPS12 (NP_203527.1).
    Isotype
    IgG
    Top Product
    Discover our top product MRPS12 Primary Antibody
  • Application Notes
    WB,1:1000 - 1:2000,IHC,1:50 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))
    Alternative Name
    MRPS12 (MRPS12 Products)
    Synonyms
    MPR-S12 antibody, MT-RPS12 antibody, RPMS12 antibody, RPS12 antibody, RPSM12 antibody, AI327385 antibody, Rpms12 antibody, rps12 antibody, CG7925 antibody, Dmel\\CG7925 antibody, EG:BACH59J11.1 antibody, MRP-S12 antibody, MRPS12 antibody, S12 antibody, Tko antibody, l(1)3Ab antibody, l(1)tko antibody, mRpS12 antibody, mt-rps12 antibody, MGC64304 antibody, GB10531 antibody, mitochondrial ribosomal protein S12 antibody, technical knockout antibody, mitochondrial ribosomal protein S12 L homeolog antibody, 40S ribosomal protein S12, mitochondrial antibody, putative mitochondrial 37S ribosomal protein MRPS12 antibody, fragile site, aphidicolin type, common, fra(6)(p22.2) antibody, MRPS12 antibody, Mrps12 antibody, tko antibody, mrps12.L antibody, LOC409723 antibody, mRpS12 antibody, mrps12 antibody, CAALFM_C106070WA antibody, mrpS12 antibody, FRA6C antibody
    Background
    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene, all three variants encode the same protein.,MRPS12,MPR-S12,MT-RPS12,RPMS12,RPS12,RPSM12,Epigenetics & Nuclear Signaling,MRPS12
    Molecular Weight
    15 kDa
    Gene ID
    6183
    UniProt
    O15235
    Pathways
    Sensory Perception of Sound
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