MRPL45 antibody (AA 57-306)
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- Target See all MRPL45 Antibodies
- MRPL45 (Mitochondrial Ribosomal Protein L45 (MRPL45))
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Binding Specificity
- AA 57-306
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MRPL45 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- MQHARKAGLV IPPEKSDRSI HLACTAGIFD AYVPPEGDAR ISSLSKEGLI ERTERMKKTM ASQVSIRRIK DYDANFKIKD FPEKAKDIFI EAHLCLNNSD HDRLHTLVTE HCFPDMTWDI KYKTVRWSFV ESLEPSHVVQ VRCSSMMNQG NVYGQITVRM HTRQTLAIYD RFGRLMYGQE DVPKDVLEYV VFEKQLTNPY GSWRMHTKIV PPWAPPKQPI LKTVMIPGPQ LKPEEEYEEA QGEAQKPQLA
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 57-306 of human MRPL45 (NP_115727.5).
- Isotype
- IgG
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MRPL45 (Mitochondrial Ribosomal Protein L45 (MRPL45))
- Alternative Name
- MRPL45 (MRPL45 Products)
- Synonyms
- L45mt antibody, MRP-L45 antibody, 2600005P05Rik antibody, AU043542 antibody, R75241 antibody, mrlp45 antibody, mitochondrial ribosomal protein L45 antibody, mitochondrial ribosomal protein L45 L homeolog antibody, Mrpl45 antibody, MRPL45 antibody, mrpl45.L antibody
- Background
- Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q.,MRPL45,L45mt,MRP-L45,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitochondrial translation,Nucleotide metabolism,MRPL45
- Molecular Weight
- 35 kDa
- Gene ID
- 84311
- UniProt
- Q9BRJ2
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