MRGPRX1 antibody (AA 263-322)
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- Target See all MRGPRX1 Antibodies
- MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))
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Binding Specificity
- AA 263-322
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MRGPRX1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LNSSANPIIY FFVGSFRQRQ NRQNLKLVLQ RALQDASEVD EGGGQLPEEI LELSGSRLEQ
- Cross-Reactivity
- Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 263-322 of human MRGPRX1 (NP_671732.3).
- Isotype
- IgG
- Top Product
- Discover our top product MRGPRX1 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))
- Alternative Name
- MRGPRX1 (MRGPRX1 Products)
- Synonyms
- GPCR antibody, MRGX1 antibody, SNSR4 antibody, MrgC11 antibody, Mrgprc11 antibody, Snsr1 antibody, MAS related GPR family member X1 antibody, MAS-related GPR, member X1 antibody, MRGPRX1 antibody, Mrgprx1 antibody
- Background
- Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22 and BAM (8-22(PubMed:26582731. BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alphaq proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.,MRGPRX1,GPCR,MGRG2,MRGX1,SNSR4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),MRGPRX1
- Molecular Weight
- 36 kDa
- Gene ID
- 259249
- UniProt
- Q96LB2
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