MPZL1 antibody (AA 1-269)

Catalog No. ABIN6143978

Product Details anti-MPZL1 Antibody

Target: MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))

Binding Specificity: AA 1-269

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPZL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MAASAGAGAV IAAPDSRRWL WSVLAAALGL LTAGVSALEV YTPKEIFVAN GTQGKLTCKF KSTSTTGGLT SVSWSFQPEG ADTTVSFFHY SQGQVYLGNY PPFKDRISWA GDLDKKDASI NIENMQFIHN GTYICDVKNP PDIVVQPGHI RLYVVEKENL PVFPVWVVVG IVTAVVLGLT LLISMILAVL YRRKNSKRDY TGCSTSESLS PVKQAPRKSP SDTEGLVKSL PSGSHQGPVI YAQLDHSGGH HSDKINKSES VVYADIRKN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-269 of human MPZL1 (NP_003944.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MPZL1

Target: MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))

Alternative Name: MPZL1 (MPZL1 Products)

Background: Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role, it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.,MPZL1,MPZL1b,PZR,PZR1b,PZRa,PZRb,Signal Transduction,MPZL1

Molecular Weight: 12 kDa/15 kDa/22 kDa/28 kDa/29 kDa

Gene ID: 9019

UniProt: O95297