Myeloperoxidase antibody (AA 50-310)

Catalog No. ABIN6143964

Product Details anti-Myeloperoxidase Antibody

Target: Myeloperoxidase (MPO)

Binding Specificity: AA 50-310

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myeloperoxidase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: APAVLGEVDT SLVLSSMEEA KQLVDKAYKE RRESIKQRLR SGSASPMELL SYFKQPVAAT RTAVRAADYL HVALDLLERK LRSLWRRPFN VTDVLTPAQL NVLSKSSGCA YQDVGVTCPE QDKYRTITGM CNNRRSPTLG ASNRAFVRWL PAEYEDGFSL PYGWTPGVKR NGFPVALARA VSNEIVRFPT DQLTPDQERS LMFMQWGQLL DHDLDFTPEP AARASFVTGV NCETSCVQQP PCFPLKIPPN DPRIKNQADC I

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-310 of human Myeloperoxidase (MPO) (NP_000241.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Myeloperoxidase

Target: Myeloperoxidase (MPO)

Alternative Name: MPO (MPO Products)

Background: Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.,MPO,Cancer,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Blood,MPO

Molecular Weight: 73 kDa/83 kDa/87 kDa

Gene ID: 4353

UniProt: P05164

Pathways: Chromatin Binding