MICB antibody (AA 23-108)

Catalog No. ABIN6143831

Product Details anti-MICB Antibody

Target: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Binding Specificity: AA 23-108

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MICB antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AEPHSLRYNL MVLSQDGSVQ SGFLAEGHLD GQPFLRYDRQ KRRAKPQGQW AENVLGAKTW DTETEDLTEN GQDLRRTLTH IKDQKG

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-108 of human MICB (NP_005922.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MICB

Target: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Alternative Name: MICB (MICB Products)

Background: This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.,MICB,PERB11.2,Immunology & Inflammation,MICB

Molecular Weight: 4 kDa/37 kDa/42 kDa

Gene ID: 4277

UniProt: Q29980

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response