MDC1 antibody (AA 1-350)
-
- Target See all MDC1 Antibodies
- MDC1 (Mdc1 (MDC1))
-
Binding Specificity
- AA 1-350
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This MDC1 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- MEDTQAIDWD VEEEEETEQS SESLRCNVEP VGRLHIFSGA HGPEKDFPLH LGKNVVGRMP DCSVALPFPS ISKQHAEIEI LAWDKAPILR DCGSLNGTQI LRPPKVLSPG VSHRLRDQEL ILFADLLCQY HRLDVSLPFV SRGPLTVEET PRVQGETQPQ RLLLAEDSEE EVDFLSERRM VKKSRTTSSS VIVPESDEEG HSPVLGGLGP PFAFNLNSDT DVEEGQQPAT EEASSAARRG ATVEAKQSEA EVVTEIQLEK DQPLVKERDN DTKVKRGAGN GVVPAGVILE RSQPPGEDSD TDVDDDSRPP GRPAEVHLER AQPFGFIDSD TDAEEERIPA TPVVIPMKKR
- Cross-Reactivity
- Human
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human MDC1 (NP_055456.2).
- Isotype
- IgG
- Top Product
- Discover our top product MDC1 Primary Antibody
-
anti-Mdc1 (MDC1) antibody
MDC1 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Mdc1 (MDC1) (AA 1-100) antibodyMDC1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Mdc1 (MDC1) (AA 31-130) antibodyMDC1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Mdc1 (MDC1) (N-Term) antibodyMDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 unconjugated
anti-Mdc1 (MDC1) (N-Term) antibody (HRP)MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 HRP
anti-Mdc1 (MDC1) (N-Term) antibody (FITC)MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 FITC
anti-Mdc1 (MDC1) (N-Term) antibody (Alkaline Phosphatase (AP))MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 Alkaline Phosphatase (AP)
anti-Mdc1 (MDC1) (N-Term) antibody (Biotin)MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 Biotin
anti-Mdc1 (MDC1) (N-Term) antibody (PE)MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 PE
anti-Mdc1 (MDC1) (N-Term) antibody (APC)MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 APC
-
- Application Notes
- WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- MDC1 (Mdc1 (MDC1))
- Alternative Name
- MDC1 (MDC1 Products)
- Synonyms
- 6820401C03 antibody, AA413496 antibody, Nfbd1 antibody, mKIAA0170 antibody, NFBD1 antibody, mediator of DNA damage checkpoint 1 antibody, mediator of DNA-damage checkpoint 1 antibody, Mdc1 antibody, MDC1 antibody
- Background
- The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.,MDC1,NFBD1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,MDC1
- Molecular Weight
- 116 kDa/195 kDa/197 kDa/226 kDa
- Gene ID
- 9656
- UniProt
- Q14676
-
