MBNL2 antibody (AA 160-260)

Catalog No. ABIN6143603

Product Details anti-MBNL2 Antibody

Target: MBNL2 (Muscleblind-Like 2 (MBNL2))

Binding Specificity: AA 160-260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBNL2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PPVTVPGSTA TQKLLRTDKL EVCREFQRGN CARGETDCRF AHPADSTMID TSDNTVTVCM DYIKGRCMRE KCKYFHPPAH LQAKIKAAQH QANQAAVAAQ A

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 160-260 of human MBNL2 (NP_659002.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MBNL2

Target: MBNL2 (Muscleblind-Like 2 (MBNL2))

Alternative Name: MBNL2 (MBNL2 Products)

Synonyms: 1110002M11Rik antibody, AI047808 antibody, AI837313 antibody, AI849185 antibody, AL118326 antibody, MBLL antibody, R75232 antibody, mKIAA4072 antibody, wu:fj89c04 antibody, MBLL39 antibody, PRO2032 antibody, muscleblind like splicing factor 2 antibody, muscleblind-like splicing regulator 2 antibody, muscleblind like splicing regulator 2 antibody, Mbnl2 antibody, mbnl2 antibody, MBNL2 antibody

Background: This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.,MBNL2,MBLL,MBLL39,PRO2032,Epigenetics & Nuclear Signaling,RNA Binding,MBNL2

Molecular Weight: 39 kDa/40 kDa

Gene ID: 10150

UniProt: Q5VZF2