MARCO antibody (AA 421-520)

Catalog No. ABIN6143559

Product Details anti-MARCO Antibody

Target: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Binding Specificity: AA 421-520

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCO antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: SVSVRIVGSS NRGRAEVYYS GTWGTICDDE WQNSDAIVFC RMLGYSKGRA LYKVGAGTGQ IWLDNVQCRG TESTLWSCTK NSWGHHDCSH EEDAGVECSV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 421-520 of human MARCO (NP_006761.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MARCO

Target: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Alternative Name: MARCO (MARCO Products)

Background: The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.,MARCO,SCARA2,SR-A6,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,MARCO

Molecular Weight: 43 kDa/52 kDa

Gene ID: 8685

UniProt: Q9UEW3

Pathways: Activation of Innate immune Response