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MAPK14 antibody (AA 1-360)
MAPK14
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MAPK14 Antibody
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Target
See all MAPK14 Antibodies
MAPK14
(Mitogen-Activated Protein Kinase 14 (MAPK14))
Binding Specificity
All epitopes for MAPK14 antibodies
AA 1-360
Reactivity
All reactivities for MAPK14 antibodies
Human
Host
All hosts for MAPK14 antibodies
Rabbit
Clonality
All clonalities for MAPK14 antibodies
Polyclonal
Conjugate
All conjugates for MAPK14 antibodies
This MAPK14 antibody is un-conjugated
Application
All applications for MAPK14 antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Sequence
MSQERPTFYR QELNKTIWEV PERYQNLSPV GSGAYGSVCA AFDTKTGLRV AVKKLSRPFQ SIIHAKRTYR ELRLLKHMKH ENVIGLLDVF TPARSLEEFN DVYLVTHLMG ADLNNIVKCQ KLTDDHVQFL IYQILRGLKY IHSADIIHRD LKPSNLAVNE DCELKILDFG LARHTDDEMT GYVATRWYRA PEIMLNWMHY NQTVDIWSVG CIMAELLTGR TLFPGTDHID QLKLILRLVG TPGAELLKKI SSESARNYIQ SLTQMPKMNF ANVFIGANPL AVDLLEKMLV LDSDKRITAA QALAHAYFAQ YHDPDDEPVA DPYDQSFESR DLLIDEWKSL TYDEVISFVP PPLDQEEMES
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human p38 MAPK (NP_620581.1).
Isotype
IgG
Top Product
Discover our top product MAPK14 Primary Antibody
Alternatives
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anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 141-240) antibody
MAPK14
Reactivity: Human, Mouse, Rat, Rabbit
WB, ELISA, IHC (p), FACS, ICC, IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB,1:500 - 1:1000,IHC,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
References for anti-MAPK14 antibody (ABIN6143525)
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He, Zhao, Anees, Li, Ashraf, Chen, Song, Chen, Cao, Ye : "p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes. " in: Frontiers in cellular and infection microbiology , Vol. 7 , pp. 271 , (2018 ) (PubMed ).
Oyagbemi, Omobowale, Ochigbo, Asenuga, Ola-Davies, Ajibade, Saba, Adedapo : "Polyphenol-Rich Fraction of Parquetina nigrescens Mitigates Dichlorvos-Induced Cardiorenal Dysfunction Through Reduction in Cardiac Nitrotyrosine and Renal p38 Expressions in Wistar Rats. " in: Journal of dietary supplements , Vol. 15 , Issue 3 , pp. 269-284 , (2018 ) (PubMed ).
Target Details for MAPK14
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Target
MAPK14
(Mitogen-Activated Protein Kinase 14 (MAPK14))
Alternative Name
MAPK14 (MAPK14 Products )
Synonyms
CSBP antibody, CSBP1 antibody, CSBP2 antibody, CSPB1 antibody, EXIP antibody, Mxi2 antibody, PRKM14 antibody, PRKM15 antibody, RK antibody, SAPK2A antibody, p38 antibody, p38ALPHA antibody, CRK1 antibody, Csbp1 antibody, Csbp2 antibody, Exip antibody, Hog antibody, Prkm14 antibody, Prkm15 antibody, Sapk2A antibody, p38Hog antibody, p38alpha antibody, p38b antibody, zp38b antibody, MAPK14 antibody, 186F5S antibody, BG:DS00797.3 antibody, CG7393 antibody, D-p38 antibody, D-p38 MAPK antibody, D-p38b antibody, Dm p38b antibody, Dmel\\CG7393 antibody, Dmp38b antibody, Dp38 antibody, Dp38b antibody, ESTS:186F5S antibody, Mpk34C antibody, anon-sts23 antibody, dp38b antibody, p38 MAPK antibody, p38 beta antibody, p38B antibody, p38Kb antibody, p38beta antibody, Crk1 antibody, p38-alpha antibody, p38MAPK antibody, p38a antibody, csbp antibody, mapk14a antibody, mxi2 antibody, sapk2 antibody, sapk2a antibody, AP22.98 antibody, AP22_98 antibody, ATMPK14 antibody, mitogen-activated protein kinase 14 antibody, SAPK2a antibody, MAP kinase 14A antibody, MAP kinase p38a antibody, MAPK 14A antibody, fk28c03 antibody, hm:zeh1243 antibody, wu:fk28c03 antibody, zp38a antibody, P38C-CRK antibody, mitogen-activated protein kinase 14 antibody, mitogen activated protein kinase 14 antibody, mitogen-activated protein kinase 14b antibody, p38b MAP kinase antibody, mitogen-activated protein kinase 14 S homeolog antibody, mitogen-activated protein kinase 14a antibody, CRK proto-oncogene, adaptor protein antibody, MAPK14 antibody, Mapk14 antibody, mapk14b antibody, p38b antibody, mapk14.S antibody, MPK14 antibody, mapk14a antibody, CRK antibody
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.,MAPK14,CSBP,CSBP1,CSBP2,CSPB1,EXIP,Mxi2,PRKM14,PRKM15,RK,SAPK2A,p38,p38ALPHA,p38 MAPK,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,Kinase,Serine/threonine kinases,Phospholipase Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Angiogenesis,MAPK14
Molecular Weight
29 kDa/34 kDa/35 kDa/41 kDa
Gene ID
1432
UniProt
Q16539
Pathways
MAPK Signaling , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Regulation of Muscle Cell Differentiation , Regulation of Cell Size , Hepatitis C , Toll-Like Receptors Cascades , Autophagy , Thromboxane A2 Receptor Signaling , BCR Signaling , S100 Proteins
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