MAP4 antibody (AA 942-1152)

Catalog No. ABIN6143505

Product Details anti-MAP4 Antibody

Target: MAP4 (Microtubule-Associated Protein 4 (MAP4))

Binding Specificity: AA 942-1152

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TENIKHQPGG GRAKVEKKTE AAATTRKPES NAVTKTAGPI ASAQKQPAGK VQIVSKKVSY SHIQSKCGSK DNIKHVPGGG NVQIQNKKVD ISKVSSKCGS KANIKHKPGG GDVKIESQKL NFKEKAQAKV GSLDNVGHLP AGGAVKTEGG GSEAPLCPGP PAGEEPAISE AAPEAGAPTS ASGLNGHPTL SGGGDQREAQ TLDSQIQETS I

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 942-1152 of human MAP4 (NP_002366.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-MAP4 antibody (ABIN6143505)

Li, Wan, Zhang, Li, Han: "Quantitative proteomic analysis and comparison of two bone marrow stromal cell lines using the SILAC method." in: Experimental hematology, Vol. 44, Issue 11, pp. 1059-1071, (2017) (PubMed).

Target Details for MAP4

Target: MAP4 (Microtubule-Associated Protein 4 (MAP4))

Alternative Name: MAP4 (MAP4 Products)

Synonyms: XMAP4 antibody, mtap4 antibody, AA407148 antibody, MAP-4 antibody, Mtap-4 antibody, Mtap4 antibody, microtubule associated protein 4 antibody, microtubule associated protein 4 L homeolog antibody, microtubule-associated protein 4 antibody, MAP4 antibody, map4.L antibody, Map4 antibody

Background: The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene.,MAP4,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cyclins,Cytoskeleton,Microtubules,MAP4

Molecular Weight: 10 kDa/58 kDa/85 kDa/91 kDa/102 kDa/119 kDa/121 kDa

Gene ID: 4134

UniProt: P27816

Pathways: p53 Signaling, Microtubule Dynamics