MAP3K14 antibody (AA 648-947)

Catalog No. ABIN6143497

Product Details anti-MAP3K14 Antibody

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Binding Specificity: AA 648-947

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K14 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: GGKVNRALQQ VGGLKSPWRG EYKEPRHPPP NQANYHQTLH AQPRELSPRA PGPRPAEETT GRAPKLQPPL PPEPPEPNKS PPLTLSKEES GMWEPLPLSS LEPAPARNPS SPERKATVPE QELQQLEIEL FLNSLSQPFS LEEQEQILSC LSIDSLSLSD DSEKNPSKAS QSSRDTLSSG VHSWSSQAEA RSSSWNMVLA RGRPTDTPSY FNGVKVQIQS LNGEHLHIRE FHRVKVGDIA TGISSQIPAA AFSLVTKDGQ PVRYDMEVPD SGIDLQCTLA PDGSFAWSWR VKHGQLENRP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 648-947 of human MAP3K14 (NP_003945.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MAP3K14

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Alternative Name: MAP3K14 (MAP3K14 Products)

Synonyms: FTDCR1B antibody, HS antibody, HSNIK antibody, NIK antibody, F23F1.4 antibody, F23F1_4 antibody, mitogen-activated protein kinase kinase kinase 14 antibody, Nik antibody, aly antibody, mitogen-activated protein kinase kinase kinase 14 antibody, MAP3K14 antibody, Map3k14 antibody, MAPKKK14 antibody

Background: This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.,MAP3K14,FTDCR1B,HS,HSNIK,NIK,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,MAP3K14

Molecular Weight: 104 kDa

Gene ID: 9020

UniProt: Q99558

Pathways: NF-kappaB Signaling, TCR Signaling