LMX1B antibody (AA 136-395)

Catalog No. ABIN6143280

Product Details anti-LMX1B Antibody

Target: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Binding Specificity: AA 136-395

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMX1B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YHLGCFCCCV CERQLRKGDE FVLKEGQLLC KGDYEKEKDL LSSVSPDESD SVKSEDEDGD MKPAKGQGSQ SKGSGDDGKD PRRPKRPRTI LTTQQRRAFK ASFEVSSKPC RKVRETLAAE TGLSVRVVQV WFQNQRAKMK KLARRHQQQQ EQQNSQRLGQ EVLSSRMEGM MASYTPLAPP QQQIVAMEQS PYGSSDPFQQ GLTPPQMPGN DSIFHDIDSD TSLTSLSDCF LGSSDVGSLQ ARVGNPIDRL YSMQSSYFAS

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 136-395 of human LMX1B (NP_002307.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LMX1B

Target: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Alternative Name: LMX1B (LMX1B Products)

Synonyms: LMX1.2 antibody, NPS1 antibody, LMX antibody, LMX1 antibody, LMX1.1 antibody, lmx1b antibody, lmx1b.1 antibody, Xlmx1b antibody, lmx1b.2 antibody, LIM homeobox transcription factor 1 beta antibody, LIM homeobox transcription factor 1, beta b antibody, LIM homeobox transcription factor 1, beta, gene 1 S homeolog antibody, LIM homeobox transcription factor 1, beta a antibody, LMX1B antibody, Lmx1b antibody, lmx1bb antibody, lmx1b.1.S antibody, lmx1ba antibody

Background: This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,LMX1B,LMX1.2,NPS1,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,LMX1B

Molecular Weight: 44 kDa/45 kDa

Gene ID: 4010

UniProt: O60663

Pathways: Dopaminergic Neurogenesis