LHCGR antibody (AA 200-360)

Catalog No. ABIN6143185

Product Details anti-LHCGR Antibody

Target: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Binding Specificity: AA 200-360

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LHCGR antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: TSLELKENVH LEKMHNGAFR GATGPKTLDI SSTKLQALPS YGLESIQRLI ATSSYSLKKL PSRETFVNLL EATLTYPSHC CAFRNLPTKE QNFSHSISEN FSKQCESTVR KVNNKTLYSS MLAESELSGW DYEYGFCLPK TPRCAPEPDA FNPCEDIMGY D

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-360 of human LHCGR (NP_000224.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LHCGR

Target: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Alternative Name: LHCGR (LHCGR Products)

Background: This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.,LHCGR,HHG,LCGR,LGR2,LH/CG-R,LH/CGR,LHR,LHRHR,LSH-R,ULG5,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Neuroscience,LHCGR

Molecular Weight: 71 kDa/78 kDa

Gene ID: 3973

UniProt: P22888

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling