Lamin B Receptor antibody (AA 1-211)

Catalog No. ABIN6143105

Product Details anti-Lamin B Receptor Antibody

Target: Lamin B Receptor (LBR)

Binding Specificity: AA 1-211

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lamin B Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: MPSRKFADGE VVRGRWPGSS LYYEVEILSH DSTSQLYTVK YKDGTELELK ENDIKPLTSF RQRKGGSTSS SPSRRRGSRS RSRSRSPGRP PKSARRSASA SHQADIKEAR REVEVKLTPL ILKPFGNSIS RYNGEPEHIE RNDAPHKNTQ EKFSLSQESS YIATQYSLRP RREEVKLKEI DSKEEKYVAK ELAVRTFEVT PIRAKDLEFG G

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human LBR (NP_002287.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Lamin B Receptor

Target: Lamin B Receptor (LBR)

Alternative Name: LBR (LBR Products)

Background: The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.,LBR,DHCR14B,LMN2R,PHA,TDRD18,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Intermediate Filaments,Endocrine & Metabolism,Lipid Metabolism,LBR

Molecular Weight: 70 kDa

Gene ID: 3930

UniProt: Q14739