LAP3 antibody (AA 260-519)

Catalog No. ABIN6143087

Product Details anti-LAP3 Antibody

Target: LAP3 (Cytosol Aminopeptidase (LAP3))

Binding Specificity: AA 260-519

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAP3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VFLEIHYKGS PNANEPPLVF VGKGITFDSG GISIKASANM DLMRADMGGA ATICSAIVSA AKLNLPINII GLAPLCENMP SGKANKPGDV VRAKNGKTIQ VDNTDAEGRL ILADALCYAH TFNPKVILNA ATLTGAMDVA LGSGATGVFT NSSWLWNKLF EASIETGDRV WRMPLFEHYT RQVVDCQLAD VNNIGKYRSA GACTAAAFLK EFVTHPKWAH LDIAGVMTNK DEVPYLRKGM TGRPTRTLIE FLLRFSQDNA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 260-519 of human LAP3 (NP_056991.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LAP3

Target: LAP3 (Cytosol Aminopeptidase (LAP3))

Alternative Name: LAP3 (LAP3 Products)

Synonyms: LAP antibody, LAPEP antibody, PEPS antibody, 2410015L10Rik antibody, AA410100 antibody, LAP-3 antibody, Lap antibody, Lapep antibody, Pep-7 antibody, Pep-S antibody, Pep7 antibody, Peps antibody, cytosol aminopeptidase antibody, leucine aminopeptidase 3 antibody, pepA antibody, Plabr_1567 antibody, Dester_0800 antibody, Weevi_0186 antibody, Marky_0570 antibody, Halhy_2623 antibody, FsymDg_3217 antibody, Flexsi_2186 antibody, Runsl_3980 antibody, lap3 antibody, LAP3 antibody, Lap3 antibody

Background: Cytolosic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+ ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+, it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status.,LAP3,HEL-S-106,LAP,LAPEP,PEPS,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Cardiovascular,Blood,Blood Pressure regulation,LAP3

Molecular Weight: 52 kDa/56 kDa

Gene ID: 51056

UniProt: P28838