Kallikrein 7 antibody (AA 30-253)

Catalog No. ABIN6142961

Product Details anti-Kallikrein 7 Antibody

Target: Kallikrein 7 (KLK7)

Binding Specificity: AA 30-253

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IIDGAPCARG SHPWQVALLS GNQLHCGGVL VNERWVLTAA HCKMNEYTVH LGSDTLGDRR AQRIKASKSF RHPGYSTQTH VNDLMLVKLN SQARLSSMVK KVRLPSRCEP PGTTCTVSGW GTTTSPDVTF PSDLMCVDVK LISPQDCTKV YKDLLENSML CAGIPDSKKN ACNGDSGGPL VCRGTLQGLV SWGTFPCGQP NDPGVYTQVC KFTKWINDTM KKHR

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-253 of human KLK7 (NP_644806.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Kallikrein 7

Target: Kallikrein 7 (KLK7)

Alternative Name: KLK7 (KLK7 Products)

Synonyms: Prss6 antibody, SCCE antibody, PRSS6 antibody, hK7 antibody, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) antibody, kallikrein-related peptidase 7 antibody, kallikrein related peptidase 7 antibody, Klk7 antibody, KLK7 antibody

Background: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.,KLK7,PRSS6,SCCE,hK7,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Ubiquitin,KLK7

Molecular Weight: 19 kDa/27 kDa

Gene ID: 5650

UniProt: P49862

Pathways: Complement System