KDM5B antibody (AA 784-883)

Catalog No. ABIN6142802

Product Details anti-KDM5B Antibody

Target: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Binding Specificity: AA 784-883

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM5B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: EESEMKKFPD NDLLRHLRLV TQDAEKCASV AQQLLNGKRQ TRYRSGGGKS QNQLTVNELR QFVTQLYALP CVLSQTPLLK DLLNRVEDFQ QHSQKLLSEE

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 784-883 of human KDM5B (NP_006609.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KDM5B

Target: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Alternative Name: KDM5B (KDM5B Products)

Background: This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants.,KDM5B,CT31,JARID1B,PLU-1,PLU1,PPP1R98,PUT1,RBBP2H1A,RBP2-H1,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Demethylation,Nuclear Receptor Signaling,KDM5B

Molecular Weight: 175 kDa/179 kDa

Gene ID: 10765

UniProt: Q9UGL1

Pathways: Warburg Effect