KDM4C antibody (AA 350-570)

Catalog No. ABIN6142798

Product Details anti-KDM4C Antibody

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Binding Specificity: AA 350-570

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM4C antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PASTPEVKAW LQRRRKVRKA SRSFQCARST SKRPKADEEE EVSDEVDGAE VPNPDSVTDD LKVSEKSEAA VKLRNTEASS EEESSASRMQ VEQNLSDHIK LSGNSCLSTS VTEDIKTEDD KAYAYRSVPS ISSEADDSIP LSSGYEKPEK SDPSELSWPK SPESCSSVAE SNGVLTEGEE SDVESHGNGL EPGEIPAVPS GERNSFKVPS IAEGENKTSK S

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-570 of human KDM4C (NP_055876.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KDM4C

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Alternative Name: KDM4C (KDM4C Products)

Background: This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants.,GASC1,JHDM3C,JMJD2C,TDRD14C,KDM4C,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Demethylation,KDM4C

Molecular Weight: 91 kDa/94 kDa/118 kDa/119 kDa

Gene ID: 23081

UniProt: Q9H3R0

Pathways: Nuclear Hormone Receptor Binding, Warburg Effect