KARS antibody (AA 298-597)

Catalog No. ABIN6142683

Product Details anti-KARS Antibody

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Binding Specificity: AA 298-597

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KARS antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: IAPELYHKML VVGGIDRVYE IGRQFRNEGI DLTHNPEFTT CEFYMAYADY HDLMEITEKM VSGMVKHITG SYKVTYHPDG PEGQAYDVDF TPPFRRINMV EELEKALGMK LPETNLFETE ETRKILDDIC VAKAVECPPP RTTARLLDKL VGEFLEVTCI NPTFICDHPQ IMSPLAKWHR SKEGLTERFE LFVMKKEICN AYTELNDPMR QRQLFEEQAK AKAAGDDEAM FIDENFCTAL EYGLPPTAGW GMGIDRVAMF LTDSNNIKEV LLFPAMKPED KKENVATTDT LESTTVGTSV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 298-597 of human LysRS/LysRS/KARS (NP_005539.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KARS

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Alternative Name: KARS (KARS Products)

Synonyms: CG12141 antibody, Dmel\\CG12141 antibody, KRS antibody, LysRS antibody, cb530 antibody, wu:fa16h02 antibody, zgc:92483 antibody, kars antibody, MGC53345 antibody, kars2 antibody, krs antibody, krs-1 antibody, KARS antibody, Tb06.28P18.190 antibody, CMTRIB antibody, DFNB89 antibody, KARS1 antibody, KARS2 antibody, AA589550 antibody, AL024334 antibody, AL033315 antibody, AL033367 antibody, D8Ertd698e antibody, D8Wsu108e antibody, mKIAA0070 antibody, Lysyl-tRNA synthetase antibody, lysyl-tRNA synthetase antibody, lysyl-tRNA synthetase S homeolog antibody, lysyl-tRNA synthetase L homeolog antibody, LysRS antibody, kars antibody, kars.S antibody, kars.L antibody, Bm1_16500 antibody, lysS antibody, Taci_1118 antibody, Tpau_1737 antibody, Arch_0261 antibody, Trad_2960 antibody, Spirs_3699 antibody, KARS antibody, LOC100280510 antibody, Tb927.6.1510 antibody, Kars antibody

Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,KARS,CMTRIB,DFNB89,KARS1,KARS2,KRS,Epigenetics & Nuclear Signaling,KARS

Molecular Weight: 68 kDa/71 kDa

Gene ID: 3735

UniProt: Q15046