KARS antibody (AA 298-597)
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- Target See all KARS Antibodies
- KARS (Lysyl-tRNA Synthetase (KARS))
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Binding Specificity
- AA 298-597
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KARS antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- IAPELYHKML VVGGIDRVYE IGRQFRNEGI DLTHNPEFTT CEFYMAYADY HDLMEITEKM VSGMVKHITG SYKVTYHPDG PEGQAYDVDF TPPFRRINMV EELEKALGMK LPETNLFETE ETRKILDDIC VAKAVECPPP RTTARLLDKL VGEFLEVTCI NPTFICDHPQ IMSPLAKWHR SKEGLTERFE LFVMKKEICN AYTELNDPMR QRQLFEEQAK AKAAGDDEAM FIDENFCTAL EYGLPPTAGW GMGIDRVAMF LTDSNNIKEV LLFPAMKPED KKENVATTDT LESTTVGTSV
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 298-597 of human LysRS/LysRS/KARS (NP_005539.1).
- Isotype
- IgG
- Top Product
- Discover our top product KARS Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- KARS (Lysyl-tRNA Synthetase (KARS))
- Alternative Name
- KARS (KARS Products)
- Background
- Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,KARS,CMTRIB,DFNB89,KARS1,KARS2,KRS,Epigenetics & Nuclear Signaling,KARS
- Molecular Weight
- 68 kDa/71 kDa
- Gene ID
- 3735
- UniProt
- Q15046
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