JTB antibody (AA 31-105)
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- Target See all JTB Antibodies
- JTB (Jumping Translocation Breakpoint (JTB))
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Binding Specificity
- AA 31-105
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This JTB antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- EAPVQEEKLS ASTSNLPCWL VEEFVVAEEC SPCSNFRAKT TPECGPTGYV EKITCSSSKR NEFKSCRSAL MEQRL
- Cross-Reactivity
- Human, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 31-105 of human JTB (NP_006685.1).
- Isotype
- IgG
- Top Product
- Discover our top product JTB Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- JTB (Jumping Translocation Breakpoint (JTB))
- Alternative Name
- JTB (JTB Products)
- Synonyms
- HJTB antibody, HSPC222 antibody, PAR antibody, hJT antibody, Gm622 antibody, JTB antibody, jumping translocation breakpoint antibody, JTB antibody, Jtb antibody
- Background
- Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC, a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential (By similarity.,JTB,HJTB,HSPC222,PAR,hJT,Cell Biology & Developmental Biology,JTB
- Molecular Weight
- 13 kDa/16 kDa
- Gene ID
- 10899
- UniProt
- O76095
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