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JTB antibody (AA 31-105)

JTB Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6142668
  • Target See all JTB Antibodies
    JTB (Jumping Translocation Breakpoint (JTB))
    Binding Specificity
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-105
    Reactivity
    • 16
    • 9
    Human
    Host
    • 22
    • 2
    Rabbit
    Clonality
    • 22
    • 1
    Polyclonal
    Conjugate
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This JTB antibody is un-conjugated
    Application
    • 13
    • 13
    • 11
    • 9
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    EAPVQEEKLS ASTSNLPCWL VEEFVVAEEC SPCSNFRAKT TPECGPTGYV EKITCSSSKR NEFKSCRSAL MEQRL
    Cross-Reactivity
    Human, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 31-105 of human JTB (NP_006685.1).
    Isotype
    IgG
    Top Product
    Discover our top product JTB Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    JTB (Jumping Translocation Breakpoint (JTB))
    Alternative Name
    JTB (JTB Products)
    Synonyms
    HJTB antibody, HSPC222 antibody, PAR antibody, hJT antibody, Gm622 antibody, JTB antibody, jumping translocation breakpoint antibody, JTB antibody, Jtb antibody
    Background
    Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC, a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential (By similarity.,JTB,HJTB,HSPC222,PAR,hJT,Cell Biology & Developmental Biology,JTB
    Molecular Weight
    13 kDa/16 kDa
    Gene ID
    10899
    UniProt
    O76095
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