IMPDH1 antibody (AA 434-563)
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- Target See all IMPDH1 Antibodies
- IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))
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Binding Specificity
- AA 434-563
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IMPDH1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- MMGSLLAATT EAPGEYFFSD GVRLKKYRGM GSLDAMEKSS SSQKRYFSEG DKVKIAQGVS GSIQDKGSIQ KFVPYLIAGI QHGCQDIGAR SLSVLRSMMY SGELKFEKRT MSAQIEGGVH GLHSYEKRLY
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 434-563 of human IMPDH1 (NP_899066.1).
- Isotype
- IgG
- Top Product
- Discover our top product IMPDH1 Primary Antibody
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- Application Notes
- WB,1:1000 - 1:2000,IF,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))
- Alternative Name
- IMPDH1 (IMPDH1 Products)
- Background
- The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.,IMPDH1,IMPD,IMPD1,IMPDH-I,LCA11,RP10,sWSS2608,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Nucleotide metabolism,Neuroscience,IMPDH1
- Molecular Weight
- 52 kDa/54 kDa/55 kDa/60 kDa/63 kDa/64 kDa
- Gene ID
- 3614
- UniProt
- P20839
- Pathways
- Ribonucleoside Biosynthetic Process
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