IMPDH1 antibody (AA 434-563)

Catalog No. ABIN6142433

Product Details anti-IMPDH1 Antibody

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Binding Specificity: AA 434-563

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMPDH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: MMGSLLAATT EAPGEYFFSD GVRLKKYRGM GSLDAMEKSS SSQKRYFSEG DKVKIAQGVS GSIQDKGSIQ KFVPYLIAGI QHGCQDIGAR SLSVLRSMMY SGELKFEKRT MSAQIEGGVH GLHSYEKRLY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 434-563 of human IMPDH1 (NP_899066.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IMPDH1

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Alternative Name: IMPDH1 (IMPDH1 Products)

Synonyms: IMPD antibody, IMPD1 antibody, LCA11 antibody, RP10 antibody, sWSS2608 antibody, B930086D20Rik antibody, IMPD 1 antibody, IMPDH 1 antibody, D3 antibody, IMPD 1b antibody, IMPDH 1b antibody, IMPDH1 antibody, id:ibd5035 antibody, si:dkey-31f5.7 antibody, wu:fa09h11 antibody, wu:fa99c03 antibody, zgc:113446 antibody, imp antibody, imp1 antibody, imp2 antibody, IMPD 1a antibody, IMPDH 1a antibody, zgc:91911 antibody, inosine monophosphate dehydrogenase 1 antibody, inosine-5'-monophosphate dehydrogenase 1 antibody, IMP (inosine 5'-monophosphate) dehydrogenase 1b antibody, IMP (inosine 5'-monophosphate) dehydrogenase 1 antibody, IMP (inosine 5'-monophosphate) dehydrogenase 1a antibody, IMPDH1 antibody, Impdh1 antibody, LOC100442769 antibody, impdh1 antibody, impdh1b antibody, impdh1.L antibody, impdh1a antibody

Background: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.,IMPDH1,IMPD,IMPD1,IMPDH-I,LCA11,RP10,sWSS2608,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Nucleotide metabolism,Neuroscience,IMPDH1

Molecular Weight: 52 kDa/54 kDa/55 kDa/60 kDa/63 kDa/64 kDa

Gene ID: 3614

UniProt: P20839

Pathways: Ribonucleoside Biosynthetic Process