IL18BP antibody (AA 31-194)

Catalog No. ABIN6142329

Product Details anti-IL18BP Antibody

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Binding Specificity: AA 31-194

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL18BP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: TPVSQTTTAA TASVRSTKDP CPSQPPVFPA AKQCPALEVT WPEVEVPLNG TLSLSCVACS RFPNFSILYW LGNGSFIEHL PGRLWEGSTS RERGSTGTQL CKALVLEQLT PALHSTNFSC VLVDPEQVVQ RHVVLAQLWA GLRATLPPTQ EALPSSHSSP QQQG

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 31-194 of human IL18BP (NP_001138529.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IL18BP

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Alternative Name: IL18BP (IL18BP Products)

Synonyms: IL18BP antibody, IL-18BP antibody, Igifbp antibody, MC54L antibody, IL18BPa antibody, interleukin 18 binding protein antibody, IL18BP antibody, Il18bp antibody

Background: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.,IL18BP,IL18BPa,Immunology & Inflammation,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL18BP

Molecular Weight: 12 kDa/17 kDa/21 kDa

Gene ID: 10068

UniProt: O95998