IGFBP7 antibody (AA 27-282)

Catalog No. ABIN6142263

Product Details anti-IGFBP7 Antibody

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Binding Specificity: AA 27-282

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGFBP7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SSSDTCGPCE PASCPPLPPL GCLLGETRDA CGCCPMCARG EGEPCGGGGA GRGYCAPGME CVKSRKRRKG KAGAAAGGPG VSGVCVCKSR YPVCGSDGTT YPSGCQLRAA SQRAESRGEK AITQVSKGTC EQGPSIVTPP KDIWNVTGAQ VYLSCEVIGI PTPVLIWNKV KRGHYGVQRT ELLPGDRDNL AIQTRGGPEK HEVTGWVLVS PLSKEDAGEY ECHASNSQGQ ASASAKITVV DALHEIPVKK GEGAEL

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 27-282 of human IGFBP7 (NP_001544.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IGFBP7

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Alternative Name: IGFBP7 (IGFBP7 Products)

Synonyms: zgc:85888 antibody, AGM antibody, FSTL2 antibody, IBP-7 antibody, IGFBP-7 antibody, IGFBP-7v antibody, IGFBPRP1 antibody, MAC25 antibody, PSF antibody, RAMSVPS antibody, TAF antibody, Fstl2 antibody, Mac25 antibody, insulin like growth factor binding protein 7 antibody, insulin-like growth factor binding protein 7 antibody, IGFBP7 antibody, igfbp7 antibody, Igfbp7 antibody

Background: This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307).,IGFBP7,AGM,FSTL2,IBP-7,IGFBP-7,IGFBP-7v,IGFBPRP1,MAC25,PSF,RAMSVPS,TAF,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,IGFBP7

Molecular Weight: 28 kDa/29 kDa

Gene ID: 3490

UniProt: Q16270

Pathways: Growth Factor Binding