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IGF2R antibody (AA 2327-2491)

IGF2R Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6142247
  • Target See all IGF2R Antibodies
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    Binding Specificity
    • 16
    • 13
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2327-2491
    Reactivity
    • 88
    • 36
    • 19
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 67
    • 23
    Rabbit
    Clonality
    • 66
    • 24
    Polyclonal
    Conjugate
    • 46
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IGF2R antibody is un-conjugated
    Application
    • 34
    • 33
    • 28
    • 23
    • 13
    • 13
    • 13
    • 11
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    YKKERRETVI SKLTTCCRRS SNVSYKYSKV NKEEETDENE TEWLMEEIQL PPPRQGKEGQ ENGHITTKSV KALSSLHGDD QDSEDEVLTI PEVKVHSGRG AGAESSHPVR NAQSNALQER EDDRVGLVRG EKARKGKSSS AQQKTVSSTK LVSFHDDSDE DLLHI
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 2327-2491 of human Cation-independent M6PR (Cation-independent M6PR (IGF2R)) (NP_000867.2).
    Isotype
    IgG
    Top Product
    Discover our top product IGF2R Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    Alternative Name
    IGF2R (IGF2R Products)
    Synonyms
    CD222 antibody, CIMPR antibody, M6P-R antibody, MPR1 antibody, MPRI antibody, AI661837 antibody, CI-MPR antibody, M6P/IGF2R antibody, Mpr300 antibody, mpri antibody, cd222 antibody, cimpr antibody, m6p-r antibody, insulin like growth factor 2 receptor antibody, insulin-like growth factor 2 receptor antibody, IGF2R antibody, Igf2r antibody, igf2r antibody
    Background
    This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele, however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611).,IGF2R,CD222,CI-M6PR,CIMPR,M6P-R,M6P/IGF2R,MPR 300,MPR1,MPR300,MPRI,Signal Transduction,Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,IGF2R
    Molecular Weight
    274 kDa
    Gene ID
    3482
    UniProt
    P11717
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