IARS antibody (AA 1158-1262)

Catalog No. ABIN6142113

Product Details anti-IARS Antibody

Target: IARS (Isoleucyl-tRNA Synthetase (IARS))

Binding Specificity: AA 1158-1262

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IARS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SAPSLINSSS TLLCQYINLQ LLNAKPQECL MGTVGTLLLE NPLGQNGLTH QGLLYEAAKV FGLRSRKLKL FLNETQTQEI TEDIPVKTLN MKTVYVSVLP TTADF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1158-1262 of human IARS (NP_002152.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IARS

Target: IARS (Isoleucyl-tRNA Synthetase (IARS))

Alternative Name: IARS (IARS Products)

Synonyms: fi46h05 antibody, zgc:63790 antibody, wu:fi46h05 antibody, K19E20.18 antibody, K19E20_18 antibody, ovule abortion 2 antibody, ECK0027 antibody, ilvS antibody, JW0024 antibody, An08g06770 antibody, AO090012000505 antibody, 2510016L12Rik antibody, AI327140 antibody, AU044614 antibody, E430001P04Rik antibody, ILRS antibody, Iarsl antibody, IARS1 antibody, ILERS antibody, IRS antibody, PRO0785 antibody, isoleucyl-tRNA synthetase antibody, tRNA synthetase class I (I, L, M and V) family protein antibody, isoleucine--tRNA ligase antibody, isoleucyl-tRNA synthetase, cytoplasmic antibody, isoleucine-tRNA synthetase antibody, iars antibody, IARS antibody, OVA2 antibody, ileS antibody, MBAR_RS19160 antibody, Rmag_0340 antibody, ANI_1_964074 antibody, CHLREDRAFT_106327 antibody, EDI_049880 antibody, OE_RS08520 antibody, AOR_1_1912194 antibody, Iars antibody

Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found.,IARS,GRIDHH,IARS1,ILERS,ILRS,IRS,PRO0785,Epigenetics & Nuclear Signaling,IARS

Molecular Weight: 144 kDa

Gene ID: 3376

UniProt: P41252