Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

HUS1 antibody (AA 1-280)

HUS1 Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6142085
  • Target See all HUS1 Antibodies
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-280
    Reactivity
    • 51
    • 28
    • 15
    Human
    Host
    • 62
    • 4
    Rabbit
    Clonality
    • 65
    • 1
    Polyclonal
    Conjugate
    • 23
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HUS1 antibody is un-conjugated
    Application
    • 31
    • 27
    • 13
    • 13
    • 9
    • 9
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    Sequence
    MKFRAKIVDG ACLNHFTRIS NMIAKLAKTC TLRISPDKLN FILCDKLANG GVSMWCELEQ ENFFNEFQME GVSAENNEIY LELTSENLSR ALKTAQNARA LKIKLTNKHF PCLTVSVELL SMSSSSRIVT HDIPIKVIPR KLWKDLQEPV VPDPDVSIYL PVLKTMKSVV EKMKNISNHL VIEANLDGEL NLKIETELVC VTTHFKDLGN PPLASESTHE DRNVEHMAEV HIDIRKLLQF LAGQQVNPTK ALCNIVNNKM VHFDLLHEDV SLQYFIPALS
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human HUS1 (NP_004498.1).
    Isotype
    IgG
    Top Product
    Discover our top product HUS1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:100,IP,1:50 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    Alternative Name
    HUS1 (HUS1 Products)
    Synonyms
    hHUS1 antibody, mHus1 antibody, XHus1 antibody, hus1 antibody, HUS1 checkpoint clamp component antibody, checkpoint clamp complex protein Hus1 antibody, HUS1 checkpoint clamp component L homeolog antibody, HUS1 antibody, Hus1 antibody, hus1 antibody, hus1.L antibody
    Background
    The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants.,HUS1,hHUS1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Signal Transduction,Kinase,HUS1
    Molecular Weight
    29 kDa/31 kDa
    Gene ID
    3364
    UniProt
    O60921
You are here:
Support