HTRA1 antibody (AA 22-160)

Catalog No. ABIN6142078

Product Details anti-HTRA1 Antibody

Target: HTRA1 (HtrA Serine Peptidase 1 (HTRA1))

Binding Specificity: AA 22-160

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTRA1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AQLSRAGRSA PLAAGCPDRC EPARCPPQPE HCEGGRARDA CGCCEVCGAP EGAACGLQEG PCGEGLQCVV PFGVPASATV RRRAQAGLCV CASSEPVCGS DANTYANLCQ LRAASRRSER LHRPPVIVLQ RGACGQGQE

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-160 of human HTRA1 (NP_002766.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HTRA1

Target: HTRA1 (HtrA Serine Peptidase 1 (HTRA1))

Alternative Name: HTRA1 (HTRA1 Products)

Background: This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.,HTRA1,ARMD7,CADASIL2,CARASIL,HtrA,L56,ORF480,PRSS11,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,HTRA1

Molecular Weight: 51 kDa

Gene ID: 5654

UniProt: Q92743

Pathways: Growth Factor Binding