HRG antibody (AA 20-260)

Catalog No. ABIN6141987

Product Details anti-HRG Antibody

Target: HRG (Histidine-Rich Glycoprotein (HRG))

Binding Specificity: AA 20-260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRG antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SPTDCSAVEP EAEKALDLIN KRRRDGYLFQ LLRIADAHLD RVENTTVYYL VLDVQESDCS VLSRKYWNDC EPPDSRRPSE IVIGQCKVIA TRHSHESQDL RVIDFNCTTS SVSSALANTK DSPVLIDFFE DTERYRKQAN KALEKYKEEN DDFASFRVDR IERVARVRGG EGTGYFVDFS VRNCPRHHFP RHPNVFGFCR ADLFYDVEAL DLESPKNLVI NCEVFDPQEH ENINGVPPHL G

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-260 of human HRG (NP_000403.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HRG

Target: HRG (Histidine-Rich Glycoprotein (HRG))

Alternative Name: HRG (HRG Products)

Background: This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.,HRG,HPRG,HRGP,THPH11,Cardiovascular,Angiogenesis,Blood,Coagulation,Serum Proteins,HRG

Molecular Weight: 59 kDa

Gene ID: 3273

UniProt: P04196