HNRNPL antibody (AA 282-589)

Catalog No. ABIN6141915

Product Details anti-HNRNPL Antibody

Target: HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

Binding Specificity: AA 282-589

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: TWDYTNPNLS GQGDPGSNPN KRQRQPPLLG DHPAEYGGPH GGYHSHYHDE GYGPPPPHYE GRRMGPPVGG HRRGPSRYGP QYGHPPPPPP PPEYGPHADS PVLMVYGLDQ SKMNCDRVFN VFCLYGNVEK VKFMKSKPGA AMVEMADGYA VDRAITHLNN NFMFGQKLNV CVSKQPAIMP GQSYGLEDGS CSYKDFSESR NNRFSTPEQA AKNRIQHPSN VLHFFNAPLE VTEENFFEIC DELGVKRPSS VKVFSGKSER SSSGLLEWES KSDALETLGF LNHYQMKNPN GPYPYTLKLC FSTAQHAS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 282-589 of human HNRNPL (NP_001524.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HNRNPL

Target: HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

Alternative Name: HNRNPL (HNRNPL Products)

Synonyms: HNRPL antibody, hnRNP-L antibody, zgc:55429 antibody, HNRNPL antibody, hnrpl antibody, C79783 antibody, D830027H13Rik antibody, Hnrpl antibody, hnrnp-L antibody, heterogeneous nuclear ribonucleoprotein L antibody, HNRNPL antibody, hnrpl antibody, hnrnpl antibody, Hnrnpl antibody

Background: Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.,HNRNPL,HNRPL,P/OKcl.14,hnRNP-L,Epigenetics & Nuclear Signaling,RNA Binding,HNRNPL

Molecular Weight: 50 kDa/64 kDa

Gene ID: 3191

UniProt: P14866