EPAS1 antibody (AA 588-870)
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- Target See all EPAS1 Antibodies
- EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
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Binding Specificity
- AA 588-870
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EPAS1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- FQQQLESKKT EPEHRPMSSI FFDAGSKASL PPCCGQASTP LSSMGGRSNT QWPPDPPLHF GPTKWAVGDQ RTEFLGAAPL GPPVSPPHVS TFKTRSAKGF GARGPDVLSP AMVALSNKLK LKRQLEYEEQ AFQDLSGGDP PGGSTSHLMW KRMKNLRGGS CPLMPDKPLS ANVPNDKFTQ NPMRGLGHPL RHLPLPQPPS AISPGENSKS RFPPQCYATQ YQDYSLSSAH KVSGMASRLL GPSFESYLLP ELTRYDCEVN VPVLGSSTLL QGGDLLRALD QAT
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 588-870 of human EPAS1/HIF2alpha (NP_001421.2).
- Isotype
- IgG
- Top Product
- Discover our top product EPAS1 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
- Alternative Name
- EPAS1 (EPAS1 Products)
- Background
- This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.,EPAS1,ECYT4,HIF2A,HLF,MOP2,PASD2,bHLHe73,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Invasion and Metastasis,Endocrine & Metabolism,Nucleotide metabolism,Molecular processes,Cardiovascular,Angiogenesis,Hypoxia,HIF,EPAS1
- Molecular Weight
- 96 kDa
- Gene ID
- 2034
- UniProt
- Q99814
- Pathways
- Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
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