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Hexosaminidase A antibody (AA 270-529)
HEXA
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Hexosaminidase A Antibody
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Target
See all Hexosaminidase A (HEXA) Antibodies
Hexosaminidase A (HEXA)
Binding Specificity
All epitopes for Hexosaminidase A antibodies
AA 270-529
Reactivity
All reactivities for Hexosaminidase A antibodies
Human
Host
All hosts for Hexosaminidase A antibodies
Rabbit
Clonality
All clonalities for Hexosaminidase A antibodies
Polyclonal
Conjugate
All conjugates for Hexosaminidase A antibodies
This Hexosaminidase A antibody is un-conjugated
Application
All applications for Hexosaminidase A antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Sequence
IPGLLTPCYS GSEPSGTFGP VNPSLNNTYE FMSTFFLEVS SVFPDFYLHL GGDEVDFTCW KSNPEIQDFM RKKGFGEDFK QLESFYIQTL LDIVSSYGKG YVVWQEVFDN KVKIQPDTII QVWREDIPVN YMKELELVTK AGFRALLSAP WYLNRISYGP DWKDFYIVEP LAFEGTPEQK ALVIGGEACM WGEYVDNTNL VPRLWPRAGA VAERLWSNKL TSDLTFAYER LSHFRCELLR RGVQAQPLNV GFCEQEFEQT
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 270-529 of human HEXA (NP_000511.2).
Isotype
IgG
Top Product
Discover our top product HEXA Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for Hexosaminidase A
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Target
Hexosaminidase A (HEXA)
Alternative Name
HEXA (HEXA Products )
Synonyms
TSD antibody, fc04h11 antibody, wu:fc04h11 antibody, wu:fv09f06 antibody, si:dkey-35i22.2 antibody, HEXA antibody, Hex-1 antibody, zgc:112084 antibody, hexosaminidase subunit alpha antibody, hexosaminidase B (beta polypeptide) antibody, CUGBP Elav-like family member 6 antibody, hexosaminidase A antibody, hexosaminidase A (alpha polypeptide) antibody, beta-hexosaminidase subunit alpha-like antibody, HEXA antibody, hexb antibody, CELF6 antibody, Hexa antibody, hexa antibody, LOC100228061 antibody
Background
This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.,HEXA,TSD,Neuroscience,Neurodegenerative Diseases,HEXA
Molecular Weight
19 kDa/60 kDa
Gene ID
3073
UniProt
P06865
Pathways
Sensory Perception of Sound , Glycosaminoglycan Metabolic Process
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