HES1 antibody (AA 151-280)

Catalog No. ABIN6141726

Product Details anti-HES1 Antibody

Target: HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

Binding Specificity: AA 151-280

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HES1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NAMTYPGQPH PALQAPPPPP PGPGGPQHAP FAPPPPLVPI PGGAAPPPGG APCKLGSQAG EAAKVFGGFQ VVPAPDGQFA FLIPNGAFAH SGPVIPVYTS NSGTSVGPNA VSPSSGPSLT ADSMWRPWRN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 151-280 of human HES1 (NP_005515.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-HES1 antibody (ABIN6141726)

Xu, Chen, Huang, Cheng, Wu, Wang, Li, Yu, Chen: "Epigenetic modification of TLE1 induce abnormal differentiation in diabetic mice intestinal epithelium." in: Molecular and cellular biochemistry, Vol. 438, Issue 1-2, pp. 85-96, (2018) (PubMed).

Target Details for HES1

Target: HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

Alternative Name: HES1 (HES1 Products)

Synonyms: HES-1 antibody, HHL antibody, HRY antibody, bHLHb39 antibody, Hry antibody, HAIRY1 antibody, c-hairy1A antibody, Xhairy1 antibody, hairy1 antibody, hes1 antibody, Xhairy-1 antibody, Xlh1 antibody, hes family bHLH transcription factor 1 antibody, hairy and enhancer of split 1 (Drosophila) antibody, hes family bHLH transcription factor 4 antibody, hes family bHLH transcription factor 1 S homeolog antibody, hes family bHLH transcription factor 1 L homeolog antibody, HES1 antibody, Hes1 antibody, HES4 antibody, hes1.S antibody, hes1.L antibody

Background: This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.,HES1,HES-1,HHL,HRY,bHLHb39,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,HES1

Molecular Weight: 29 kDa

Gene ID: 3280

UniProt: Q14469

Pathways: DNA Damage Repair