HADHB antibody (AA 34-270)

Catalog No. ABIN6141589

Product Details anti-HADHB Antibody

Target: HADHB (Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB))

Binding Specificity: AA 34-270

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HADHB antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: AAPAVQTKTK KTLAKPNIRN VVVVDGVRTP FLLSGTSYKD LMPHDLARAA LTGLLHRTSV PKEVVDYIIF GTVIQEVKTS NVAREAALGA GFSDKTPAHT VTMACISANQ AMTTGVGLIA SGQCDVIVAG GVELMSDVPI RHSRKMRKLM LDLNKAKSMG QRLSLISKFR FNFLAPELPA VSEFSTSETM GHSADRLAAA FAVSRLEQDE YALRSHSLAK KAQDEGLLSD VVPFKVP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 34-270 of human HADHB (NP_000174.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:10 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-HADHB antibody (ABIN6141589)

Fan, Long, Yan, Wang, Shi, Bao, Hu, Li, Chen, Zheng, Yan: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." in: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).

Target Details for HADHB

Target: HADHB (Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB))

Alternative Name: HADHB (HADHB Products)

Synonyms: ECHB antibody, MTPB antibody, TP-BETA antibody, thiolase antibody, fb14g10 antibody, wu:fb14g10 antibody, zgc:56274 antibody, 4930479F15Rik antibody, Mtpb antibody, Hadhb antibody, hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta antibody, hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta S homeolog antibody, hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit antibody, hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit antibody, HADHB antibody, hadhb.S antibody, Hadhb antibody, hadhb antibody

Background: This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described.,HADHB,ECHB,MSTP029,MTPB,TP-BETA,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Lipid Metabolism,HADHB

Molecular Weight: 48 kDa/51 kDa

Gene ID: 3032

UniProt: P55084

Pathways: Monocarboxylic Acid Catabolic Process