gtse1 antibody, MGC81588 antibody, MGC89498 antibody, GTSE1 antibody, fb70b04 antibody, fj88g09 antibody, wu:fb70b04 antibody, wu:fj88g09 antibody, wu:fy65d12 antibody, MGC114722 antibody, B99 antibody, Gtse-1 antibody, RGD1563164 antibody, G2 and S-phase expressed 1 S homeolog antibody, G2 and S-phase expressed 1 antibody, G-2 and S-phase expressed 1 antibody, G2 and S-phase expressed 1 L homeolog antibody, G two S phase expressed protein 1 antibody, gtse1.S antibody, gtse1 antibody, GTSE1 antibody, gtse1.L antibody, Gtse1 antibody
Background
The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.,GTSE1,B99,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,GTSE1