2010015D03Rik antibody, 2610111I01Rik antibody, 5330403M05Rik antibody, GTF3A antibody, TFIIIA antibody, gtf3a antibody, zgc:111799 antibody, AP2 antibody, general transcription factor III A antibody, general transcription factor IIIA antibody, general transcription factor 3A L homeolog antibody, general transcription factor IIIAa antibody, Gtf3a antibody, GTF3A antibody, gtf3a.L antibody, gtf3aa antibody
Background
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.,GTF3A,AP2,TFIIIA,Epigenetics & Nuclear Signaling,Transcription Factors,GTF3A