GSTM3 antibody (AA 101-225)
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- Target See all GSTM3 Antibodies
- GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))
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Binding Specificity
- AA 101-225
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GSTM3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- VDIIENQVMD FRTQLIRLCY SSDHEKLKPQ YLEELPGQLK QFSMFLGKFS WFAGEKLTFV DFLTYDILDQ NRIFDPKCLD EFPNLKAFMC RFEALEKIAA YLQSDQFCKM PINNKMAQWG NKPVC
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 101-225 of human GSTM3 (NP_000840.2).
- Isotype
- IgG
- Top Product
- Discover our top product GSTM3 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))
- Alternative Name
- GSTM3 (GSTM3 Products)
- Synonyms
- GST5 antibody, GSTB antibody, GSTM3-3 antibody, GTM3 antibody, Fsc2 antibody, mGSTM5 antibody, glutathione S-transferase mu 3 antibody, glutathione S-transferase Mu 3 antibody, glutathione S-transferase, mu 3 antibody, GSTM3 antibody, Gstm3 antibody, LOC479911 antibody
- Background
- Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants.,GSTM3,GST5,GSTB,GSTM3-3,GTM3,Cancer,Signal Transduction,Endocrine & Metabolism,Drug metabolism,GSTM3
- Molecular Weight
- 26 kDa
- Gene ID
- 2947
- UniProt
- P21266
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