GRPEL2 antibody (AA 33-225)

Catalog No. ABIN6141437

Product Details anti-GRPEL2 Antibody

Target: GRPEL2 (GrpE-Like 2, Mitochondrial (GRPEL2))

Binding Specificity: AA 33-225

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRPEL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: STATQRTAGE DCRSEDPPDE LGPPLAERAL RVKAVKLEKE VQDLTVRYQR AIADCENIRR RTQRCVEDAK IFGIQSFCKD LVEVADILEK TTECISEESE PEDQKLTLEK VFRGLLLLEA KLKSVFAKHG LEKLTPIGDK YDPHEHELIC HVPAGVGVQP GTVALVRQDG YKLHGRTIRL ARVEVAVESQ RRL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 33-225 of human GRPEL2 (NP_689620.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-GRPEL2 antibody (ABIN6141437)

Wu, Xiong, Li, Yang, Ge et al.: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).

Target Details for GRPEL2

Target: GRPEL2 (GrpE-Like 2, Mitochondrial (GRPEL2))

Alternative Name: GRPEL2 (GRPEL2 Products)

Synonyms: mt-GrpE2 antibody, mt-Grpel2 antibody, Afap1l1 antibody, Mt-GrpE2 antibody, GrpE-like 2, mitochondrial antibody, GrpE like 2, mitochondrial antibody, Grpel2 antibody, GRPEL2 antibody

Background: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive and monomeric (active forms of mt-HSP70 (By similarity.,GRPEL2,Mt-GrpE#2,GrpE like 2,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,GRPEL2

Molecular Weight: 14 kDa/25 kDa

Gene ID: 134266

UniProt: Q8TAA5