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Metabotropic Glutamate Receptor 4 antibody (AA 33-290)

GRM4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6141425
  • Target See all Metabotropic Glutamate Receptor 4 (GRM4) Antibodies
    Metabotropic Glutamate Receptor 4 (GRM4) (Glutamate Receptor, Metabotropic 4 (GRM4))
    Binding Specificity
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 33-290
    Reactivity
    • 18
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 17
    • 1
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Metabotropic Glutamate Receptor 4 antibody is un-conjugated
    Application
    • 10
    • 9
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    KPKGHPHMNS IRIDGDITLG GLFPVHGRGS EGKPCGELKK EKGIHRLEAM LFALDRINND PDLLPNITLG ARILDTCSRD THALEQSLTF VQALIEKDGT EVRCGSGGPP IITKPERVVG VIGASGSSVS IMVANILRLF KIPQISYAST APDLSDNSRY DFFSRVVPSD TYQAQAMVDI VRALKWNYVS TVASEGSYGE SGVEAFIQKS REDGGVCIAQ SVKIPREPKA GEFDKIIRRL LETSNARAVI IFANEDDI
    Cross-Reactivity
    Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 33-290 of human GRM4 (NP_000832.1).
    Isotype
    IgG
    Top Product
    Discover our top product GRM4 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Metabotropic Glutamate Receptor 4 (GRM4) (Glutamate Receptor, Metabotropic 4 (GRM4))
    Alternative Name
    GRM4 (GRM4 Products)
    Synonyms
    GPRC1D antibody, MGLUR4 antibody, mGlu4 antibody, Gprc1d antibody, mGluR4 antibody, glutamate metabotropic receptor 4 antibody, glutamate receptor, metabotropic 4 antibody, GRM4 antibody, Grm4 antibody
    Background
    L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene.,GRM4,GPRC1D,MGLUR4,mGlu4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Apoptosis,Neuroscience,GRM4
    Molecular Weight
    83 kDa/86 kDa/87 kDa/88 kDa/101 kDa
    Gene ID
    2914
    UniProt
    Q14833
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