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GREM1 antibody (AA 44-143)

GREM1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6141382
  • Target See all GREM1 Antibodies
    GREM1 (Gremlin 1 (GREM1))
    Binding Specificity
    • 20
    • 15
    • 14
    • 10
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 44-143
    Reactivity
    • 77
    • 44
    • 22
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 83
    • 8
    • 1
    Rabbit
    Clonality
    • 84
    • 8
    Polyclonal
    Conjugate
    • 37
    • 13
    • 11
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GREM1 antibody is un-conjugated
    Application
    • 78
    • 42
    • 29
    • 13
    • 13
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Sequence
    ERKYLKRDWC KTQPLKQTIH EEGCNSRTII NRFCYGQCNS FYIPRHIRKE EGSFQSCSFC KPKKFTTMMV TLNCPELQPP TKKKRVTRVK QCRCISIDLD
    Cross-Reactivity
    Human
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 44-143 of human GREM1 (NP_001178252.1).
    Isotype
    IgG
    Top Product
    Discover our top product GREM1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GREM1 (Gremlin 1 (GREM1))
    Alternative Name
    GREM1 (GREM1 Products)
    Synonyms
    grem1 antibody, MGC136702 antibody, zgc:136702 antibody, GREM1 antibody, drm antibody, pig2 antibody, dand2 antibody, ihg-2 antibody, gremlin antibody, Cktsf1b1 antibody, Drm antibody, Grem antibody, ld antibody, gremlin-1 antibody, CKTSF1B1 antibody, DAND2 antibody, DRM antibody, GREMLIN antibody, IHG-2 antibody, cktsf1b1 antibody, gremlin 1a, DAN family BMP antagonist antibody, gremlin 1, DAN family BMP antagonist antibody, gremlin 1 antibody, gremlin 1, DAN family BMP antagonist L homeolog antibody, grem1a antibody, GREM1 antibody, LOC662541 antibody, grem1 antibody, Grem1 antibody, grem1.L antibody
    Background
    This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,GREM1,C15DUPq,CKTSF1B1,CRAC1,CRCS4,DAND2,DRM,DUP15q,GREMLIN,HMPS,HMPS1,IHG-2,MPSH,PIG2,gremlin-1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,Immunology & Inflammation,Cytokines,Stem Cells,Embryonic Stem Cells,GREM1
    Molecular Weight
    16 kDa/20 kDa
    Gene ID
    26585
    UniProt
    O60565
    Pathways
    Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location
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