Golgin A2 (GOLGA2) (AA 20-300) antibody

Catalog No. ABIN6141264

Product Details

Target: Golgin A2 (GOLGA2)

Binding Specificity: AA 20-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequence: SKLAAAKKKL REYQQRNSPG VPTGAKKKKK IKNGSNPETT TSGGCHSPED TPKDNAATLQ PSDDTVLPGG VPSPGASLTS MAASQNHDAD NVPNLMDETK TFSSTESLRQ LSQQLNGLVC ESATCVNGEG PASSANLKDL ESRYQQLAVA LDSSYVTNKQ LNITIEKLKQ QNQEITDQLE EEKKECHQKQ GALREQLQVH IQTIGILVSE KAELQTALAH TQHAARQKEG ESEDLASRLQ YSRRRVGELE RALSAVSTQQ KKADRYNKEL TKERDALRLE L

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human GM130 (NP_004477.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References

Zheng, Wu, Wei, Wang, Zhang: "The release and transmission of amyloid precursor protein via exosomes." in: Neurochemistry international, Vol. 114, pp. 18-25, (2018) (PubMed).

Zheng, Pu, Chen, Guo, Pan, Zhang, Zhang, Sun, Zhang: "Exosomes Secreted from HEK293-APP Swe/Ind Cells Impair the Hippocampal Neurogenesis." in: Neurotoxicity research, Vol. 32, Issue 1, pp. 82-93, (2018) (PubMed).

Zheng, Pu, Chen, Mao, Guo, Pan, Zhang, Zhang, Sun, Zhang: "Plasma Exosomes Spread and Cluster Around β-Amyloid Plaques in an Animal Model of Alzheimer's Disease." in: Frontiers in aging neuroscience, Vol. 9, pp. 12, (2017) (PubMed).

Target Details

Target: Golgin A2 (GOLGA2)

Alternative Name: GOLGA2 (GOLGA2 Products)

Synonyms: gm130 antibody, MGC81213 antibody, AW555139 antibody, GM130 antibody, mKIAA4150 antibody, Gm130 antibody, golgin A2 S homeolog antibody, golgin A2 antibody, golgi autoantigen, golgin subfamily a, 2 antibody, golga2.S antibody, GOLGA2 antibody, Golga2 antibody

Background: The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined.,GOLGA2,GM130,golgin A2,Signal Transduction,GOLGA2

Molecular Weight: 70 kDa/113 kDa

Gene ID: 2801

UniProt: Q08379

Pathways: SARS-CoV-2 Protein Interactome