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GLUD1 antibody (AA 54-240)

GLUD1 Reactivity: Human WB, IHC, IP, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6141157
  • Target See all GLUD1 Antibodies
    GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))
    Binding Specificity
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 54-240
    Reactivity
    • 36
    • 17
    • 16
    • 14
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 41
    • 9
    • 1
    Rabbit
    Clonality
    • 41
    • 10
    Polyclonal
    Conjugate
    • 29
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GLUD1 antibody is un-conjugated
    Application
    • 31
    • 23
    • 18
    • 10
    • 9
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    Sequence
    SEAVADREDD PNFFKMVEGF FDRGASIVED KLVEDLRTRE SEEQKRNRVR GILRIIKPCN HVLSLSFPIR RDDGSWEVIE GYRAQHSQHR TPCKGGIRYS TDVSVDEVKA LASLMTYKCA VVDVPFGGAK AGVKINPKNY TDNELEKITR RFTMELAKKG FIGPGIDVPA PDMSTGEREM SWIADTY
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 54-240 of human GLUD1 (NP_005262.1).
    Isotype
    IgG
    Top Product
    Discover our top product GLUD1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))
    Alternative Name
    GLUD1 (GLUD1 Products)
    Background
    This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.,GLUD1,GDH,GDH1,GLUD,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Amino acid metabolism,GLUD1
    Molecular Weight
    42 kDa/46 kDa/61 kDa
    Gene ID
    2746
    UniProt
    P00367
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Warburg Effect
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